The “Eugenio Medea” Institute is a Scientific Institute for Research, Hospitalization and Health Care. It was officially recognized in 1985 and it specializes in neurological and neuropsychological diseases of the developmental age, focusing on research, treatment and training. Institute Medea aims at creating synergies between scientific research and hospitalization and care in order to promote the dignity and the quality of life of our young patients and their families. In particular, the scientific activity of 0-3 Center for the at-Risk Infant, where the IMPROVE PRETERM project coordinated by Dr Cuttini is developing, is focused on research projects in the developmental and psycho-biological field with particular attention on the impact that clinical conditions, adverse experiences and relational environment can have on the socio-emotional development of the infant. Specifically, one of main focus of the 0-3 Center for the at-risk infant is to promote interdisciplinary research and clinical services on the biological and social factors that determine the developmental outcomes of children born preterm.